BDBM50263201 CHEMBL4104819

SMILES Nc1sc(c(c1C(=O)c1ccccc1)-c1cccc(c1)C(F)(F)F)-c1ccc(cc1)C(=O)NCCCCCCNc1ncnc2n(cnc12)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key InChIKey=XLCQNEBOQXQNGA-IYRWRCLLSA-N

Data  12 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50263201   

TargetAdenosine receptor A2b(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50263201(CHEMBL4104819)
Affinity DataEC50:  95nMAssay Description:Agonist activity at human A2BAR expressed in FlpIn-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 40 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50263201(CHEMBL4104819)
Affinity DataEC50:  8.13E+4nMAssay Description:Agonist activity at A2BR in human NHVCF cells assessed as cAMP accumulation incubated for 30 mins in presence of PSB603 by LANCE cAMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50263201(CHEMBL4104819)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human A2B receptor expressed in Flp-In-CHO cells assessed as cAMP accumulation incubated for 10 mins in presence of forskolin by ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAdenosine receptor A2b(Homo sapiens (Human))
Monash University

Curated by ChEMBL
LigandPNGBDBM50263201(CHEMBL4104819)
Affinity DataEC50:  10nMAssay Description:Agonist activity at A2BR in human NHVCF cells assessed as cAMP accumulation incubated for 30 mins by LANCE cAMP assayMore data for this Ligand-Target Pair
In DepthDetails PubMed